TIS Division
Terumo Interventional Systems

Expanding the potential of vascular treatment to reduce patient burden

The TIS Division offers diagnostic and therapeutic catheter products used to treat illnesses in areas such as the heart and lower limbs, in the field of vascular intervention; and chemotherapy administered by catheter to the liver, in the field of interventional oncology. The TIS Division offer diverse products that serve a wide range of body areas and procedures, so that patients can benefit from more effective treatments and quality of life, and doctors can more easily perform procedures.

TIS Division Terumo Interventional Systems

The business has also promoted the interventional therapy TRI(Trans Radial Intervention), which accesses blood vessels from the wrist, which can reduce patient burden compared to other access points. Previously, TRI was used primarily for cardiovascular treatment, but in recent years Terumo has worked to develop optimal products for using TRI in peripheral and oncological areas as well, contributing to the advancement of vascular treatment.

What is vascular interventional therapy?

Human blood vessels can lose their flexibility, harden, develop thick walls, or become narrow and inhibit circulation, due to advancing age or lifestyle diseases (diabetes, high blood pressure, hyoerlipemia, etc.). When the arteries of the heart or lower limbs narrow, it can obstruct blood flow and cause heart attack or peripheral occlusive arterial disease.

One way to treat this condition is vascular intervention (interventional treatment of the coronary or peripheral arteries). In intervention, a catheter is inserted through the wrist or groin into a blood vessel and guided to the lesion (place where narrowing has occurred), where a balloon or stent is placed to expand the blood vessel from the inside and restore blood flow. Products called "access devices" are used to perform vascular intervention, including sheaths to create the opening for insertion and guidewires to lead to the lesion. Products such as drug-eluting stents (DES) are used for treatment, and imaging systems are used to monitor the lesion before and after treatment, using ultrasound or light.

Terumo provides a total lineup of devices that cover the entire treatment from start to finish, with superior usability and high effectiveness in treating patients. Going beyond simply supplying products, Terumo has also developed unique training programs as it works globally to spread minimally invasive interventional procedures that reduce patient burden.

Main Products

Note: The regulatory approval status and availability of these products differs by country or region.

Access Devices

Devices that are used to insert an interventional device at the wrist or groin and guide it to the location where therapy is to be performed

  • Introducer sheath

    Introducer sheath

  • Guidewires


  • Angiographic catheter

    Angiographic catheter

  • Vascular closure devices

    Vascular closure device

Therapeutic Devices

Devices for performing therapies such as opening up coronary or peripheral blood vessels, or preventing a cerebral aneurysm from rupturing

Coronary Intervention (Cardiology)

Drug-eluting-stent (DES)

Drug-eluting-stent (DES)

Balloon catheter

Balloon catheter

Peripheral Intervention (Endovascular)

Peripheral sten

Peripheral sten

Embolic coil system

Embolization coil system

Intravascular Imaging Systems

Imaging systems based on ultrasound or optical technology optimize procedures and support operators by acquiring luminal surface and cross-sectional images of blood vessels during PCI or PPI.

  • Intravascular ultrasound (IVUS) system

    Intravascular ultrasound (IVUS) system

  • Optical frequency domain imaging (OFDI) system

    Optical frequency domain imaging (OFDI) system

Interventional Oncology (Cancer Treatment)

"Interventional oncology" is a term referring to chemotherapy administered by an interventional device to treat cancer. One therapy used to treat liver cancer is called TACE (Transcatheter Arterial Chemo-embolization). It consists of insertion of a tiny interventional device – an extremely thin tube - called a microcatheter into the hepatic artery, which delivers nutrition to liver cancer cells; anticancer drugs and material that stops blood flow are placed there to deny blood flow and kill the cancer cells.

A subsidiary in Japan called Terumo Clinical Supply Co., Ltd. leads Terumo development and production of a wide variety of devices involved in this treatment, including micro catheter, micro balloon catheter, micro guidewire, and drug-eluting beads.

  • Interventional Oncology (Cancer Treatment)

Main Products

Note: The regulatory approval status and availability of these products differs by country or region.

Micro balloon catheter
Drug-elutable beads
  • Micro balloon catheter [photo]
  • Micro catheter
  • Micro guidewire
  • Drug-elutable beads [photo]

Procedure for catheterization (Japanese)